CAMBRIDGE, MA - May 27, 2016 - Aurora BioPharma, a company commercializing cutting-edge cancer adoptive cell immunotherapy, with CAR T cells in liquid and solid tumors, announced today its CEO, Robert Brooks, will attend the 5th Annual Marcum MicroCap Conference on June 1-2, 2016 in New York City at the Grand Hyatt Hotel.
Aurora is leading in the development of Chimeric Antigen Receptor (CAR) T therapy, Cancer Vaccines, and combinations with Checkpoint Inhibitors. AU105 is a "living-drug" CAR T agent that has shown safety and efficacy in pre-clinical and human clinical trials. A Phase 1 clinical trial was completed in 16 Glioblastoma patients, AU105 met its endpoints of safety, tumor killing efficacy, and showed promising signals of double the median historic overall survival. Aurora is planning a randomized multi-site Phase II trial of AU105 in Early Diagnosed Glioblastoma, and a Phase I/II trial in Recurrent Glioblastoma with intracranial injection. Osteosarcoma is the most common type of bone cancer in Children and Adolescents, even after radical amputation of a limb and chemotherapy, survival is poor. A Phase 1 trial in 19 Sarcoma patients was completed, AU-105 met its endpoints of safety, with strong signs of tumor killing efficacy. Aurora is planning a Phase II trial of its CAR T Cell therapy AU105 in Osteosarcoma. The Company also has an equity interest in MedVax Technologies, Inc., its p53 DC cancer vaccine MX-225 has completed a Phase II clinical trial in Small Cell Lung Cancer; and soon to complete a Phase II trial in Breast Cancer with Indoximod, an IDO inhibitor from NewLink Genetics. The Company is planning a combination trial with MX-225 and a PD-1 antibody in lung cancer with a major pharmaceutical company.
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New Paradigm in Cancer Immunotherapy
Source: Aurora BioPharma, Inc.